If I had the ability to go back in time I would use my powers to use comebacks I didn’t think of until it was too late.
Peggy is the one to get stuck in ice in and survive the century. Pepper doesn’t get rid of Extremis and becomes Rescue. Bruce Banner stays under the radar leaving Betty as the authority in gamma radiation. Jane retains some of the Aether’s powers. Thor is busy ruling Asgard, therefore Sif is the one tasked to retrieve the Tesseract. Director Fury rounds them all up along with Black Widow for his Avengers Initiative and, Barton being compromised, Maria Hill steps up as the marksman of the team.
tldr; the ladies save the world instead
With Michael Socha (Knave) joining the cast it might as well be called Once Upon a Snark.